Recent Publications
Chemoselective and Diastereoselective Intramolecular (3+2) Cycloadditions of Epoxy and Aziridinyl Enolsilanes
Chen, J. Ling, A. B. Keto, Y. He, K.-H. Low, E. H. Krenske, P Chiu (Selected as a Hot Paper)
Angew. Chem. Int. Ed. 2022, e202116099 doi.org/10.1002/anie.202116099
A soluble iron(ii)-phthalocyanine-catalyzed intramolecular C(sp3)–H amination with alkyl azides
T. You, S.H. Zeng, J. Fan, L. Wu, F. Kang, Y. Liu, C.M. Che
Chem. Commun. 2021,57, 10711 (Selected as Cover)
Towards multistate multimode landscapes in singlet fission of pentacene: the dual role of charge-transfer states
R. Walia, Z. Deng, J. Yang
Chem. Sci. 2021 DOI: 10.1039/d1sc01703a
Steering Electron‐Hole Migration Pathways using Oxygen Vacancies in Tungsten Oxides to Enhance their Photocatalytic Oxygen Evolution Performance
Z. Wei, W. Wang, W. Li, X. Bai, J. Zhao, E.C.M. Tse*, D. L. Phillips*, Y. Zhu*
Angew. Chem. Int. Ed. 2021, 60, 8236 DOI:10.1002/anie.202016170
Ferrocene-Based Metal–Organic Framework Nanosheets as a Robust Oxygen Evolution Catalyst
J. Liang, X. Gao, B. Guo, Y. Ding, J. Yan, Z. Guo, E.C.M. Tse*, J. Liu*
Angew. Chem. Int. Ed. 2021, 60, 12770 DOI:10.1002/anie.202101878
A Molecular Transformer: A π-Conjugated Macrocycle as an Adaptable Host
J. Wang, Y.-Y. Ju, K.-H. Low, Y.-Z. Tan, J. Liu*
Angew. Chem. Int. Ed. 2021, 60, 11814 DOI: 10.1002/anie.202102637
Defective Nanographenes Containing Seven-Five-Seven (7-5-7) Membered Rings
Y. Fei, Y. Fu, X. Bai, L. Du, Z. Li, H. Komber, K.-H. Low, S. Zhou, D. L. Phillips, X. Feng, J. Liu*
J. Am. Chem. Soc. 2021, 143, 2353 DOI: 10.1021/jacs.0c12116
Bio-adhesive Nanoporous Module: Toward Autonomous Gating
H. Jo, T. Kitao, A. Kimura, Y. Itoh, T. Aida*, K. Okuro*
Angew. Chem. Int. Ed. 2021, 60, 8932 DOI: 10.1002/anie.202017117
Total synthesis of mannopeptimycin via chemical ligation cyclization
J. Wang, D. Lin, M. Liu, H. Liu, Li, X.*
J. Am. Chem. Soc. 2021. 143, 12784 DOI: 10.1021/jacs.1c05922
Chemical Synthesis and Biological Evaluation of Adiponectin Collagenous Domain Glycoforms
H. Wu, Y. Zhang, Y. Li, J. Xu, Y. Wang*, X. Li*
J. Am. Chem. Soc. 2021, 143, 7808 DOI: 10.1021/jacs.1c02382
Revealing generation, migration and dissociation of electron−hole pairs and current emergence in an organic photovoltaic cell
Z. Xu, Y. Zhou, C.Y. Yam, T. Frauenheim, C. Lienau, G.H. Chen*
Sci. Adv. 2021, 7, eabf7672 DOI: 10.1126/sciadv.abf7672
Rapid Broad Spectrum Detection of Carbapenemases with a Dual Fluorogenic-Colorimetric Probe
C.W. Ma, K.K.H. Ng, B.H.C. Yam, P.L. Ho, R.Y.T. Kao, D. Yang*
J. Am. Chem. Soc. 2021, 18, 6886 DOI: 10.1021/jacs.1c00462
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance
H.B. Wang, M.J. Wang, X.H. Xu, P. Gao, Z.L. Xu, Q. Zhang, H.Y. Li, A.X. Yan, R.Y.T. Kao, H.Z. Sun*
Nat. Commun. 2021, 12, 3331 DOI: 10.1038/s41467-021-23659-y
Photoinduced Hydroarylation and Cyclization of Alkenes with Luminescent Platinum(II) Complexes
H. Cheng, T.L. Lam, Y. Liu, Z. Tang, C.M. Che*
Angew.Chem. Int. Ed. 2021, 60, 1383-1389 DOI: 10.1002/anie.202011841
C−H Activation by an Iron-Nitrido Bis-Pocket Porphyrin Species
H.X. Wang, L. Wu, B. Zheng, L. Du, W.P. To, C.H. Ko, D. L. Phillips*, C.M. Che*
Angew.Chem. Int. Ed. 2021, 60,4796 DOI: 10.1002/anie.202014191
Aggregation and Supramolecular Self-Assembly of Low-Energy Red Luminescent Alkynylplatinum(II) Complexes for RNA Detection, Nucleolus Imaging, and RNA Synthesis Inhibitor Screening
A.S.Y. Law, L.C.C. Lee, K.K.W. Lo*, V.W.W. Yam*
J. Am. Chem. Soc. 2021, 143, 5396 DOI: 10.1021/jacs.0c13327
Dual Emissive Gold(I)–Sulfido Cluster Framework Capable of Benzene–Cyclohexane Separation in the Solid State Accompanied by Luminescence Color Changes
L.Y. Yao, V.W.W. Yam*
J. Am. Chem. Soc. 2021, 143, 2558 DOI: 10.1021/jacs.0c11891
Platinum(II)-Based Host–Guest Coordination-Driven Supramolecular Co-Assembly Assisted by Pt···Pt and π–π Stacking Interactions: A Dual-Selective Luminescence Sensor for Cations and Anions
Y.S. Wong, M. Ng, M.C.L. Yeung, V.W.W. Yam*
J. Am. Chem. Soc. 2021, 143, 973 DOI: 10.1021/jacs.0c11162
A tri-functional amino acid enables mapping of binding sites for posttranslational-modification-mediated protein-protein interactions
J. Lin, X. Bao*, X.D. Li*
Mol. Cell 2021, 81, 2669 DOI: 10.1016/j.molcel.2021.04.001
Strong metal–metal Pauli repulsion leads to repulsive metallophilicity in closed-shell d8 and d10 organometallic complexes
Q. Wan*, J. Yang*, W.P. To, C.M Che*
Proc. Natl. Acad. Sci. U.S.A. 2021, 118, e2019265118 DOI: 10.1073/pnas.2019265118
Geometrical manipulation of complex supramolecular tessellations by hierarchical assembly of amphiphilic platinum(II) complexes
J.K.L. Poon, Z. Chen, S.Y.L. Leung, M.Y. Leung, V.W.W. Yam*
Proc. Natl. Acad. Sci. U.S.A. 2021, 118, e2022829118
Catalytic reductive desymmetrization of malonic esters
P. Xu, Z. Huang*
Nat. Chem. 2021, 13, 634 DOI: 10.1038/s41557-021-00715-0
Selection of DNA-encoded chemical libraries against endogenous membrane proteins on live cells
Y. Huang, L. Meng, Q. Nie, Y. Zhou, L. Chen, S. Yang, Y. M. E. Fung, X. Li, C. Huang, Y. Cao,* Y. Li,* X. Li*
Nat. Chem. 2021, 13, 77 DOI: 10.1038/s41557-020-00605-x
Department News
- 28 Jun 2023 Eminent HKU chemist Professor Hongzhe SUN receives the Royal Society of Chemistry’s 2023 Dalton Horizon Prize
- 27 Jun 2023 New Insights into Glucose Metabolism: Targeting ATP Synthase with Chromium (III) Nutritional Supplement for Improved Blood Sugar Control
- 27 Jun 2023 HKU Researcher Professor Xuechen LI award in Carbohydrate Chemistry is obviously in the field of chemistry
- 27 Jun 2023 HKU Researcher Professor Vivian W. W. YAM receives prestigious Bailar Medal
- 27 Jun 2023 HKU Chemists discover photochromic active colloids for possible new smart active materials
- 21 Feb 2023 HKU Chemical Biologists decode a histone mark important for gene regulation program that go awry in cancer
Recent Publications
Chemoselective and Diastereoselective Intramolecular (3+2) Cycloadditions of Epoxy and Aziridinyl Enolsilanes
Chen, J. Ling, A. B. Keto, Y. He, K.-H. Low, E. H. Krenske, P Chiu (Selected as a Hot Paper)
Angew. Chem. Int. Ed. 2022, e202116099 doi.org/10.1002/anie.202116099
A soluble iron(ii)-phthalocyanine-catalyzed intramolecular C(sp3)–H amination with alkyl azides
T. You, S.H. Zeng, J. Fan, L. Wu, F. Kang, Y. Liu, C.M. Che
Chem. Commun. 2021,57, 10711 (Selected as Cover)
Towards multistate multimode landscapes in singlet fission of pentacene: the dual role of charge-transfer states
R. Walia, Z. Deng, J. Yang
Chem. Sci. 2021 DOI: 10.1039/d1sc01703a
Steering Electron‐Hole Migration Pathways using Oxygen Vacancies in Tungsten Oxides to Enhance their Photocatalytic Oxygen Evolution Performance
Z. Wei, W. Wang, W. Li, X. Bai, J. Zhao, E.C.M. Tse*, D. L. Phillips*, Y. Zhu*
Angew. Chem. Int. Ed. 2021, 60, 8236 DOI:10.1002/anie.202016170
Ferrocene-Based Metal–Organic Framework Nanosheets as a Robust Oxygen Evolution Catalyst
J. Liang, X. Gao, B. Guo, Y. Ding, J. Yan, Z. Guo, E.C.M. Tse*, J. Liu*
Angew. Chem. Int. Ed. 2021, 60, 12770 DOI:10.1002/anie.202101878
A Molecular Transformer: A π-Conjugated Macrocycle as an Adaptable Host
J. Wang, Y.-Y. Ju, K.-H. Low, Y.-Z. Tan, J. Liu*
Angew. Chem. Int. Ed. 2021, 60, 11814 DOI: 10.1002/anie.202102637
Defective Nanographenes Containing Seven-Five-Seven (7-5-7) Membered Rings
Y. Fei, Y. Fu, X. Bai, L. Du, Z. Li, H. Komber, K.-H. Low, S. Zhou, D. L. Phillips, X. Feng, J. Liu*
J. Am. Chem. Soc. 2021, 143, 2353 DOI: 10.1021/jacs.0c12116
Bio-adhesive Nanoporous Module: Toward Autonomous Gating
H. Jo, T. Kitao, A. Kimura, Y. Itoh, T. Aida*, K. Okuro*
Angew. Chem. Int. Ed. 2021, 60, 8932 DOI: 10.1002/anie.202017117
Total synthesis of mannopeptimycin via chemical ligation cyclization
J. Wang, D. Lin, M. Liu, H. Liu, Li, X.*
J. Am. Chem. Soc. 2021. 143, 12784 DOI: 10.1021/jacs.1c05922
Chemical Synthesis and Biological Evaluation of Adiponectin Collagenous Domain Glycoforms
H. Wu, Y. Zhang, Y. Li, J. Xu, Y. Wang*, X. Li*
J. Am. Chem. Soc. 2021, 143, 7808 DOI: 10.1021/jacs.1c02382
Revealing generation, migration and dissociation of electron−hole pairs and current emergence in an organic photovoltaic cell
Z. Xu, Y. Zhou, C.Y. Yam, T. Frauenheim, C. Lienau, G.H. Chen*
Sci. Adv. 2021, 7, eabf7672 DOI: 10.1126/sciadv.abf7672
Rapid Broad Spectrum Detection of Carbapenemases with a Dual Fluorogenic-Colorimetric Probe
C.W. Ma, K.K.H. Ng, B.H.C. Yam, P.L. Ho, R.Y.T. Kao, D. Yang*
J. Am. Chem. Soc. 2021, 18, 6886 DOI: 10.1021/jacs.1c00462
Multi-target mode of action of silver against Staphylococcus aureus endows it with capability to combat antibiotic resistance
H.B. Wang, M.J. Wang, X.H. Xu, P. Gao, Z.L. Xu, Q. Zhang, H.Y. Li, A.X. Yan, R.Y.T. Kao, H.Z. Sun*
Nat. Commun. 2021, 12, 3331 DOI: 10.1038/s41467-021-23659-y
Photoinduced Hydroarylation and Cyclization of Alkenes with Luminescent Platinum(II) Complexes
H. Cheng, T.L. Lam, Y. Liu, Z. Tang, C.M. Che*
Angew.Chem. Int. Ed. 2021, 60, 1383-1389 DOI: 10.1002/anie.202011841
C−H Activation by an Iron-Nitrido Bis-Pocket Porphyrin Species
H.X. Wang, L. Wu, B. Zheng, L. Du, W.P. To, C.H. Ko, D. L. Phillips*, C.M. Che*
Angew.Chem. Int. Ed. 2021, 60,4796 DOI: 10.1002/anie.202014191
Aggregation and Supramolecular Self-Assembly of Low-Energy Red Luminescent Alkynylplatinum(II) Complexes for RNA Detection, Nucleolus Imaging, and RNA Synthesis Inhibitor Screening
A.S.Y. Law, L.C.C. Lee, K.K.W. Lo*, V.W.W. Yam*
J. Am. Chem. Soc. 2021, 143, 5396 DOI: 10.1021/jacs.0c13327
Dual Emissive Gold(I)–Sulfido Cluster Framework Capable of Benzene–Cyclohexane Separation in the Solid State Accompanied by Luminescence Color Changes
L.Y. Yao, V.W.W. Yam*
J. Am. Chem. Soc. 2021, 143, 2558 DOI: 10.1021/jacs.0c11891
Platinum(II)-Based Host–Guest Coordination-Driven Supramolecular Co-Assembly Assisted by Pt···Pt and π–π Stacking Interactions: A Dual-Selective Luminescence Sensor for Cations and Anions
Y.S. Wong, M. Ng, M.C.L. Yeung, V.W.W. Yam*
J. Am. Chem. Soc. 2021, 143, 973 DOI: 10.1021/jacs.0c11162
A tri-functional amino acid enables mapping of binding sites for posttranslational-modification-mediated protein-protein interactions
J. Lin, X. Bao*, X.D. Li*
Mol. Cell 2021, 81, 2669 DOI: 10.1016/j.molcel.2021.04.001
Strong metal–metal Pauli repulsion leads to repulsive metallophilicity in closed-shell d8 and d10 organometallic complexes
Q. Wan*, J. Yang*, W.P. To, C.M Che*
Proc. Natl. Acad. Sci. U.S.A. 2021, 118, e2019265118 DOI: 10.1073/pnas.2019265118
Geometrical manipulation of complex supramolecular tessellations by hierarchical assembly of amphiphilic platinum(II) complexes
J.K.L. Poon, Z. Chen, S.Y.L. Leung, M.Y. Leung, V.W.W. Yam*
Proc. Natl. Acad. Sci. U.S.A. 2021, 118, e2022829118
Catalytic reductive desymmetrization of malonic esters
P. Xu, Z. Huang*
Nat. Chem. 2021, 13, 634 DOI: 10.1038/s41557-021-00715-0
Selection of DNA-encoded chemical libraries against endogenous membrane proteins on live cells
Y. Huang, L. Meng, Q. Nie, Y. Zhou, L. Chen, S. Yang, Y. M. E. Fung, X. Li, C. Huang, Y. Cao,* Y. Li,* X. Li*
Nat. Chem. 2021, 13, 77 DOI: 10.1038/s41557-020-00605-x
Department News
-
28 Jun 2023
Eminent HKU chemist Professor Hongzhe SUN receives the Royal Society of Chemistry’s 2023 Dalton Horizon Prize
-
27 Jun 2023
New Insights into Glucose Metabolism: Targeting ATP Synthase with Chromium (III) Nutritional Supplement for Improved Blood Sugar Control
-
27 Jun 2023
HKU Researcher Professor Xuechen LI award in Carbohydrate Chemistry is obviously in the field of chemistry
-
27 Jun 2023
HKU Researcher Professor Vivian W. W. YAM receives prestigious Bailar Medal
-
27 Jun 2023
HKU Chemists discover photochromic active colloids for possible new smart active materials
-
21 Feb 2023
HKU Chemical Biologists decode a histone mark important for gene regulation program that go awry in cancer
Seminars
-
Supramolecular Chromophores: From Assembly to Photocatalysis21May2024Prof. Luka ÐorđevićDepartment of Chemistry, University of Padova, Italy5:00 - 6:00 PM (HKT), CYCP1
-
New Strategies for the Synthesis of Unusual Peptides and Alkaloids14May2024Prof. Steven L. CastleDepartment of Chemistry and Biochemistry, United States of America4:30 - 5:30 PM (HKT), CYCP1
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Deconstructive Homologation of Ethers and Amides08May2024Prof. Guangbin DongDepartment of Chemistry, The University of Chicago4:30 - 5:30 PM (HKT), CYCP1